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Browse CatalogAfamelanotide is a synthetic tridecapeptide analog of alpha-melanocyte-stimulating hormone (alpha-MSH). It is a linear peptide with a specific substitution (Nle4, D-Phe7) that gives it greater potency and longer duration of action at the MC1R receptor compared to the native hormone. This modification was a key innovation in melanocortin peptide pharmacology.
Research on Afamelanotide has primarily focused on its selective MC1R agonism and its effects on melanogenesis. Unlike Melanotan II, which is a non-selective melanocortin agonist, Afamelanotide provides more targeted MC1R activation. Published studies have investigated its effects on melanin production, DNA repair in UV-exposed skin cells, and photoprotective mechanisms. Some research has also explored its immune-modulatory properties through MC1R-mediated pathways.
NXPeptides offers Afamelanotide as a lyophilized powder, HPLC tested with purity of 97% or above. A Certificate of Analysis is provided with each order. Store the lyophilized peptide at -20C. After reconstitution, keep at 2-8C and protect from light, as the molecule can be light-sensitive.
See our reconstitution guide and storage guide for details.
Free worldwide shipping, delivered in 3 to 10 days with discrete, temperature-controlled packaging. Anonymous checkout. Contact support@nxpeptides.com or visit our contact page. Track your order and review quality standards. Research use only. Not for human consumption.
This product is verified at ≥97% purity via reverse-phase HPLC analysis. A batch-specific Certificate of Analysis (COA) documenting exact purity percentage, mass spectrometry results, and appearance is included with your order.
Store the unopened lyophilized vial at -20°C in a dry environment. Once reconstituted, divide into single-use aliquots and store frozen at -20°C. Avoid repeated freeze-thaw cycles. Properly stored lyophilized powder has a shelf life of approximately 24 to 36 months.
Add bacteriostatic water or sterile water slowly along the vial wall. Do not spray directly onto the lyophilized powder. Gently swirl until completely dissolved. Do not vortex. See our full reconstitution guide for detailed instructions and solvent selection.
Orders ship within 24 hours. Domestic delivery takes 3 to 5 business days, international 5 to 10 business days. All shipments are temperature-controlled, tracked, and shipped in discrete packaging. You can track your order here.
No. This product is sold strictly for in-vitro laboratory research purposes only. It is not intended for human consumption, veterinary use, or any in-vivo application. By purchasing, you confirm you are 21+ and will use this product only for legitimate research.
Contact our support team at support@nxpeptides.com or use our contact form. We offer full replacements or refunds for any issues with purity, quantity, or shipping damage within 30 days of delivery.
Yes. We offer volume discounts for research institutions and repeat customers. Contact us with your quantity requirements and we will provide a custom quote within 24 hours.